Epigenetic Co-Deregulation of EZH2/TET1 is a Senescence-Countering, Actionable Vulnerability in Triple-Negative Breast Cancer. [electronic resource]
Producer: 20200114Description: 761-777 p. digitalISSN:- 1838-7640
- Animals
- Antibiotics, Antineoplastic -- administration & dosage
- Apoptosis -- drug effects
- Cancer Survivors
- Cell Line, Tumor
- Cellular Senescence -- drug effects
- DNA Methylation
- DNA, Neoplasm -- metabolism
- Doxorubicin -- administration & dosage
- Drug Delivery Systems
- Enhancer of Zeste Homolog 2 Protein -- antagonists & inhibitors
- Epigenesis, Genetic
- Female
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Indazoles -- pharmacology
- Mice
- Mice, Nude
- Mixed Function Oxygenases -- antagonists & inhibitors
- Proto-Oncogene Proteins -- antagonists & inhibitors
- Pyridones -- pharmacology
- Triple Negative Breast Neoplasms -- genetics
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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