Optimal therapeutic activity of monoclonal antibodies against chikungunya virus requires Fc-FcγR interaction on monocytes. [electronic resource]
Producer: 20200406ISSN:- 2470-9468
- Animals
- Antibodies, Monoclonal, Humanized -- therapeutic use
- Antibodies, Monoclonal, Murine-Derived -- therapeutic use
- Antibodies, Neutralizing -- therapeutic use
- Antibodies, Viral -- therapeutic use
- Arthritis, Experimental -- therapy
- Chikungunya Fever -- virology
- Chikungunya virus -- immunology
- Complement Activation -- immunology
- Complement C1q -- immunology
- Disease Models, Animal
- Epitopes -- immunology
- Immunoglobulin Fc Fragments -- immunology
- Immunologic Factors -- therapeutic use
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Monocytes -- immunology
- Receptor, Interferon alpha-beta -- genetics
- Receptors, IgG -- immunology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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