Neuroprotective potential of ketamine prevents developing brain structure impairment and alteration of neurocognitive function induced via isoflurane through the PI3K/AKT/GSK-3β pathway. [electronic resource]
Producer: 20190809Description: 501-512 p. digitalISSN:- 1177-8881
- Animals
- Brain -- drug effects
- Dose-Response Relationship, Drug
- Female
- Glycogen Synthase Kinase 3 beta -- metabolism
- Isoflurane -- pharmacology
- Ketamine -- pharmacology
- Male
- Neurocognitive Disorders -- chemically induced
- Neuroprotective Agents -- pharmacology
- Phosphatidylinositol 3-Kinases -- metabolism
- Proto-Oncogene Proteins c-akt -- metabolism
- Rats
- Rats, Sprague-Dawley
- Signal Transduction -- drug effects
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Publication Type: Journal Article
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