En bloc and segmental deletions of human XIST reveal X chromosome inactivation-involving RNA elements. [electronic resource]
Producer: 20191125Description: 3875-3887 p. digitalISSN:- 1362-4962
- Alternative Splicing
- Animals
- Base Sequence
- CRISPR-Associated Protein 9 -- genetics
- CRISPR-Cas Systems
- Chromosomes, Human, X -- chemistry
- Clone Cells
- Exons
- Gene Editing -- methods
- Genome, Human
- Humans
- K562 Cells
- Mice
- Promoter Regions, Genetic
- RNA, Long Noncoding -- genetics
- Sequence Deletion
- Species Specificity
- Whole Genome Sequencing
- X Chromosome Inactivation
- RNA, Guide, CRISPR-Cas Systems
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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