DYRK1A regulates the recruitment of 53BP1 to the sites of DNA damage in part through interaction with RNF169. [electronic resource]
Producer: 20200413Description: 531-551 p. digitalISSN:- 1551-4005
- Animals
- CRISPR-Cas Systems -- genetics
- Cell Cycle Checkpoints -- radiation effects
- Cell Line, Tumor
- DNA Damage -- radiation effects
- DNA Repair
- Gamma Rays
- Gene Editing
- Humans
- Metabolic Networks and Pathways
- Mice
- Phosphorylation
- Protein Binding
- Protein Serine-Threonine Kinases -- deficiency
- Protein-Tyrosine Kinases -- deficiency
- RNA Interference
- RNA, Small Interfering -- metabolism
- Tumor Suppressor p53-Binding Protein 1 -- metabolism
- Ubiquitin-Protein Ligases -- antagonists & inhibitors
- Dyrk Kinases
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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