Physiologically Based Pharmacokinetic Modelling of Hyperforin to Predict Drug Interactions with St John's Wort. [electronic resource]
Producer: 20200824Description: 911-926 p. digitalISSN:- 1179-1926
- Adult
- Alprazolam -- pharmacokinetics
- Antineoplastic Agents -- pharmacokinetics
- Computer Simulation
- Cytochrome P-450 CYP2C19 -- metabolism
- Cytochrome P-450 CYP2C9 -- metabolism
- Cytochrome P-450 CYP3A -- metabolism
- Female
- Herb-Drug Interactions
- Humans
- Hypericum
- Imatinib Mesylate -- pharmacokinetics
- Intestinal Mucosa -- metabolism
- Liver -- metabolism
- Male
- Midazolam -- pharmacokinetics
- Middle Aged
- Models, Biological
- Phloroglucinol -- analogs & derivatives
- Terpenes -- pharmacokinetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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