Activation of the Lysosome-Associated Membrane Protein LAMP5 by DOT1L Serves as a Bodyguard for MLL Fusion Oncoproteins to Evade Degradation in Leukemia. [electronic resource]
Producer: 20200619Description: 2795-2808 p. digitalISSN:- 1557-3265
- Animals
- Apoptosis
- Autophagy
- Biomarkers, Tumor -- genetics
- Cell Proliferation
- Follow-Up Studies
- Gene Expression Regulation, Neoplastic
- Histone-Lysine N-Methyltransferase -- genetics
- Humans
- Leukemia -- genetics
- Lysosomal Membrane Proteins -- genetics
- Male
- Mice
- Mice, Inbred NOD
- Mice, SCID
- Myeloid-Lymphoid Leukemia Protein -- genetics
- Oncogene Proteins, Fusion -- genetics
- Prognosis
- Proteolysis
- Survival Rate
- Tumor Cells, Cultured
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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