The Smad2/3/4 complex binds miR-139 promoter to modulate TGFβ-induced proliferation and activation of human Tenon's capsule fibroblasts through the Wnt pathway. [electronic resource]
Producer: 20200526Description: 13342-13352 p. digitalISSN:- 1097-4652
- Binding Sites -- genetics
- Catenins -- antagonists & inhibitors
- Cell Proliferation
- Cicatrix -- etiology
- Fibroblasts -- cytology
- Fibrosis
- Glaucoma Drainage Implants -- adverse effects
- Humans
- MicroRNAs -- genetics
- Promoter Regions, Genetic
- Smad Proteins -- metabolism
- Smad2 Protein -- metabolism
- Smad3 Protein -- metabolism
- Smad4 Protein -- metabolism
- Tenon Capsule -- cytology
- Transforming Growth Factor beta1 -- metabolism
- Wnt Signaling Pathway
- beta Catenin -- antagonists & inhibitors
- Delta Catenin
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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