Antimalarial Drug Pyrimethamine Plays a Dual Role in Antitumor Proliferation and Metastasis through Targeting DHFR and TP. [electronic resource]
Producer: 20200312Description: 541-555 p. digitalISSN:- 1538-8514
- Antimalarials -- chemistry
- Antineoplastic Agents -- chemistry
- Cell Proliferation -- drug effects
- Humans
- Lung Neoplasms -- drug therapy
- Methotrexate -- chemistry
- Molecular Conformation
- Neoplasm Metastasis
- Protein Structure, Secondary
- Pyrimethamine -- chemistry
- Tetrahydrofolate Dehydrogenase -- chemistry
- Thymidine Phosphorylase -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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