Lentiviral Gene Therapy in HSCs Restores Lineage-Specific Foxp3 Expression and Suppresses Autoimmunity in a Mouse Model of IPEX Syndrome. [electronic resource]
Producer: 20200327Description: 309-317.e7 p. digitalISSN:- 1875-9777
- Animals
- Autoimmunity
- Cell Lineage
- Diabetes Mellitus, Type 1 -- congenital
- Diarrhea -- genetics
- Disease Models, Animal
- Forkhead Transcription Factors -- genetics
- Genes, Reporter
- Genetic Diseases, X-Linked -- genetics
- Genetic Therapy
- Hematopoietic Stem Cells -- metabolism
- Humans
- Immune System Diseases -- congenital
- Lentivirus -- genetics
- Mice
- T-Lymphocytes, Regulatory -- immunology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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