A genome-wide RNAi screen identifies the SMC5/6 complex as a non-redundant regulator of a Topo2a-dependent G2 arrest. [electronic resource]
Producer: 20191011Description: 2906-2921 p. digitalISSN:- 1362-4962
- Cell Cycle Proteins -- genetics
- Cell Line
- Chromosomal Proteins, Non-Histone -- genetics
- DNA Damage -- drug effects
- DNA Topoisomerases, Type II -- genetics
- Diketopiperazines
- Fibroblasts -- drug effects
- G2 Phase Cell Cycle Checkpoints -- genetics
- Genome, Human -- genetics
- Germ-Line Mutation -- genetics
- Humans
- Ligases -- genetics
- Multiprotein Complexes -- genetics
- Piperazines -- pharmacology
- Poly-ADP-Ribose Binding Proteins -- antagonists & inhibitors
- RNA Interference
- Sumoylation -- genetics
- Ubiquitin-Protein Ligases -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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