Curcuminoid B63 induces ROS-mediated paraptosis-like cell death by targeting TrxR1 in gastric cells. [electronic resource]
Producer: 20190403Description: 101061 p. digitalISSN:- 2213-2317
- Animals
- Antineoplastic Agents -- chemistry
- Apoptosis -- drug effects
- Cell Death -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Curcumin -- analogs & derivatives
- Disease Models, Animal
- Endoplasmic Reticulum Stress -- drug effects
- Female
- Humans
- Membrane Potential, Mitochondrial -- drug effects
- Mice
- Models, Biological
- Models, Molecular
- Molecular Targeted Therapy
- Oxidative Stress -- drug effects
- Reactive Oxygen Species -- metabolism
- Stomach Neoplasms -- drug therapy
- Structure-Activity Relationship
- Thioredoxin Reductase 1 -- antagonists & inhibitors
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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