Predicting Patient Response to the Antiarrhythmic Mexiletine Based on Genetic Variation. [electronic resource]
Producer: 20191209Description: 539-552 p. digitalISSN:- 1524-4571
- Adolescent
- Adult
- Animals
- Anti-Arrhythmia Agents -- pharmacology
- Female
- HEK293 Cells
- Humans
- Ion Channel Gating
- Long QT Syndrome -- drug therapy
- Male
- Mexiletine -- pharmacology
- Mutation, Missense
- NAV1.5 Voltage-Gated Sodium Channel -- chemistry
- Pharmacogenomic Variants
- Sodium Channel Blockers -- pharmacology
- Xenopus
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Publication Type: Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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