Tumor Microenvironment Remodeling by Intratumoral Oncolytic Vaccinia Virus Enhances the Efficacy of Immune-Checkpoint Blockade. [electronic resource]
Producer: 20200408Description: 1612-1623 p. digitalISSN:- 1557-3265
- Animals
- Antineoplastic Agents, Immunological -- pharmacology
- Biomarkers, Tumor
- CD8-Positive T-Lymphocytes -- immunology
- Cell Line, Tumor
- Combined Modality Therapy
- Disease Models, Animal
- Genetic Vectors -- administration & dosage
- Humans
- Immunomodulation -- drug effects
- Injections, Intralesional
- Lymphocytes, Tumor-Infiltrating -- immunology
- Male
- Mice
- Mice, Transgenic
- Models, Biological
- Neoplasms -- etiology
- Oncolytic Virotherapy
- Oncolytic Viruses -- genetics
- Treatment Outcome
- Tumor Microenvironment -- genetics
- Vaccinia virus -- genetics
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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