Effect of in vitro organic nitrate tolerance on relaxation, cyclic GMP accumulation, and guanylate cyclase activation by glyceryl trinitrate and the enantiomers of isoidide dinitrate. [electronic resource]
Producer: 19881104Description: 693-701 p. digitalISSN:- 0009-7330
- Animals
- Aorta -- drug effects
- Cyclic GMP -- metabolism
- Dose-Response Relationship, Drug
- Drug Tolerance
- Guanylate Cyclase -- metabolism
- Male
- Muscle, Smooth, Vascular -- drug effects
- Nitrates -- pharmacology
- Nitroglycerin -- pharmacology
- Rats
- Rats, Inbred Strains
- Stereoisomerism
- Sugar Alcohols -- pharmacology
- Vasodilation -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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