Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis. [electronic resource]
Producer: 20190528Description: 999-1012.e6 p. digitalISSN:- 1097-4164
- Adenosine Triphosphate -- metabolism
- Cryoelectron Microscopy
- HEK293 Cells
- Humans
- Hydrolysis
- Hydrophobic and Hydrophilic Interactions
- Interferon-Induced Helicase, IFIH1 -- genetics
- Interferon-beta -- genetics
- Molecular Docking Simulation
- Mutation
- Nucleic Acid Conformation
- Protein Conformation
- RNA, Double-Stranded -- metabolism
- Signal Transduction
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Video-Audio Media
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