Identification of a novel caspase cleavage site in huntingtin that regulates mutant huntingtin clearance. [electronic resource]
Producer: 20191118Description: 3190-3197 p. digitalISSN:- 1530-6860
- Animals
- Binding Sites -- genetics
- Caspase 1 -- metabolism
- HeLa Cells
- Humans
- Huntingtin Protein -- chemistry
- Huntington Disease -- genetics
- Mice
- Mutagenesis, Site-Directed
- Mutant Proteins -- chemistry
- Protein Aggregation, Pathological -- genetics
- Protein Processing, Post-Translational
- Proteolysis
- Recombinant Fusion Proteins -- chemistry
- Solubility
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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