Lysosomal oxidation of LDL alters lysosomal pH, induces senescence, and increases secretion of pro-inflammatory cytokines in human macrophages. [electronic resource]
Producer: 20200210Description: 98-110 p. digitalISSN:- 1539-7262
- Antioxidants -- metabolism
- Cell Line
- Cellular Senescence -- drug effects
- Cysteamine -- metabolism
- Cytokines -- metabolism
- Humans
- Hydrogen-Ion Concentration
- Inflammation -- metabolism
- Iron -- metabolism
- Lipid Peroxidation -- drug effects
- Lipoproteins, LDL -- pharmacology
- Lysosomes -- chemistry
- Macrophages -- cytology
- Reactive Oxygen Species -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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