Loss-of-function mutations in KIF14 cause severe microcephaly and kidney development defects in humans and zebrafish. [electronic resource]
Producer: 20200311Description: 778-795 p. digitalISSN:- 1460-2083
- Animals
- Congenital Abnormalities -- genetics
- Cytokinesis -- genetics
- Disease Models, Animal
- Female
- Fluorescent Antibody Technique
- Genes, Lethal
- Genetic Association Studies -- methods
- Genetic Loci
- Genetic Predisposition to Disease
- Humans
- Kidney -- abnormalities
- Kidney Diseases -- congenital
- Kinesins -- chemistry
- Loss of Function Mutation
- Male
- Microcephaly -- genetics
- Oncogene Proteins -- chemistry
- Pedigree
- Phenotype
- Structure-Activity Relationship
- Zebrafish
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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