Mechanism-based inactivation of the major beta-naphthoflavone-inducible isozyme of rat liver cytochrome P-450 by the chloramphenicol analog N-(2-p-nitrophenethyl)dichloroacetamide. [electronic resource]
Producer: 19880401Description: 846-51 p. digitalISSN:- 0090-9556
- Acetamides -- pharmacology
- Animals
- Benzoflavones -- pharmacology
- Chloramphenicol -- analogs & derivatives
- Cytochrome P-450 Enzyme Inhibitors
- Cytochrome P-450 Enzyme System -- biosynthesis
- Enzyme Induction -- drug effects
- Flavonoids -- pharmacology
- In Vitro Techniques
- Isoenzymes -- antagonists & inhibitors
- Male
- Microsomes, Liver -- drug effects
- Mixed Function Oxygenases -- metabolism
- NADPH-Ferrihemoprotein Reductase -- metabolism
- Oxidation-Reduction
- Rats
- Rats, Inbred Strains
- beta-Naphthoflavone
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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