Reimagining IDO Pathway Inhibition in Cancer Immunotherapy via Downstream Focus on the Tryptophan-Kynurenine-Aryl Hydrocarbon Axis. [electronic resource]
Producer: 20200408Description: 1462-1471 p. digitalISSN:- 1557-3265
- Cell Line, Tumor
- Computational Biology -- methods
- Enzyme Inhibitors -- chemistry
- Gene Expression Profiling
- Humans
- Immunomodulation
- Immunotherapy
- Indoleamine-Pyrrole 2,3,-Dioxygenase -- metabolism
- Kynurenine -- metabolism
- Models, Biological
- Neoplasms -- genetics
- Receptors, Aryl Hydrocarbon -- metabolism
- Signal Transduction -- drug effects
- Transcriptome
- Tryptophan -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review
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