Cell cycle inhibitors protect motor neurons in an organoid model of Spinal Muscular Atrophy. [electronic resource]
Producer: 20191210Description: 1100 p. digitalISSN:- 2041-4889
- CDC2 Protein Kinase -- antagonists & inhibitors
- Cell Cycle Checkpoints -- drug effects
- Cell Differentiation
- Cell Line
- Collagen -- chemistry
- Cyclin-Dependent Kinase 2 -- antagonists & inhibitors
- Cyclin-Dependent Kinase 4 -- antagonists & inhibitors
- Cyclin-Dependent Kinase 6 -- antagonists & inhibitors
- Drug Combinations
- Embryoid Bodies -- drug effects
- Gene Expression Regulation
- Humans
- Induced Pluripotent Stem Cells -- drug effects
- Laminin -- chemistry
- Models, Biological
- Motor Neurons -- drug effects
- Muscular Atrophy, Spinal -- drug therapy
- Organoids -- drug effects
- Piperazines -- pharmacology
- Primary Cell Culture
- Protein Kinase Inhibitors -- pharmacology
- Proteoglycans -- chemistry
- Pyridines -- pharmacology
- Signal Transduction
- Small Molecule Libraries -- pharmacology
- Survival of Motor Neuron 1 Protein -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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