PDGFRα monoclonal antibody: Assessment of embryo-fetal toxicity and time-dependent placental transfer of a murine surrogate antibody of olaratumab in mice. [electronic resource]
Producer: 20190621Description: 1358-1371 p. digitalISSN:- 2472-1727
- Animals
- Antibodies, Monoclonal -- metabolism
- Dose-Response Relationship, Drug
- Embryo, Mammalian
- Female
- Fetal Development -- drug effects
- Fetus
- Maternal Exposure -- adverse effects
- Mice
- Mice, Inbred Strains
- No-Observed-Adverse-Effect Level
- Organogenesis
- Pilot Projects
- Placenta
- Pregnancy
- Receptor, Platelet-Derived Growth Factor alpha -- immunology
- Toxicity Tests -- methods
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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