Defining CRISPR-Cas9 genome-wide nuclease activities with CIRCLE-seq. [electronic resource]
Producer: 20190417Description: 2615-2642 p. digitalISSN:- 1750-2799
- CRISPR-Associated Protein 9 -- genetics
- CRISPR-Cas Systems
- Cell Line, Tumor
- Clustered Regularly Interspaced Short Palindromic Repeats
- DNA, Circular -- genetics
- Gene Editing -- methods
- Gene Library
- Genome, Human
- High-Throughput Nucleotide Sequencing -- statistics & numerical data
- Humans
- Lymphocytes -- cytology
- Osteoblasts -- cytology
- RNA, Guide, CRISPR-Cas Systems -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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