Autophagy suppresses self-renewal ability and tumorigenicity of glioma-initiating cells and promotes Notch1 degradation. [electronic resource]
Producer: 20191210Description: 1063 p. digitalISSN:- 2041-4889
- Animals
- Antineoplastic Agents -- pharmacology
- Autophagy -- drug effects
- Brain Neoplasms -- drug therapy
- Calcium-Binding Proteins -- genetics
- Carcinogenesis -- drug effects
- Cell Differentiation -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Female
- Gene Expression Regulation, Neoplastic
- Glioblastoma -- drug therapy
- Humans
- Membrane Proteins -- genetics
- Mice
- Mice, Nude
- Morpholines -- pharmacology
- Neoplastic Stem Cells -- drug effects
- Proteolysis -- drug effects
- Receptor, Notch1 -- genetics
- Signal Transduction
- Sirolimus -- pharmacology
- Sodium-Potassium-Exchanging ATPase -- genetics
- Spheroids, Cellular -- drug effects
- Survival Analysis
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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