Polyphyllin I Ameliorates Collagen-Induced Arthritis by Suppressing the Inflammation Response in Macrophages Through the NF-κB Pathway. [electronic resource]
Producer: 20191025Description: 2091 p. digitalISSN:- 1664-3224
- Animals
- Ankle Joint -- diagnostic imaging
- Arthritis, Experimental -- diagnostic imaging
- Arthritis, Rheumatoid -- diagnostic imaging
- Collagen Type II -- immunology
- Diosgenin -- analogs & derivatives
- Female
- HEK293 Cells
- Humans
- I-kappa B Kinase -- immunology
- Inflammation Mediators -- immunology
- Interferon-gamma -- immunology
- Lipopolysaccharides -- immunology
- Macrophages -- drug effects
- Mice
- Mice, Inbred C57BL
- Mice, Inbred DBA
- Phosphorylation -- drug effects
- Primary Cell Culture
- RAW 264.7 Cells
- RNA, Small Interfering -- metabolism
- Signal Transduction -- drug effects
- Synovial Fluid -- drug effects
- Transcription Factor RelA -- antagonists & inhibitors
- Treatment Outcome
- X-Ray Microtomography
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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