Linagliptin inhibits high glucose-induced transdifferentiation of hypertrophic scar-derived fibroblasts to myofibroblasts via IGF/Akt/mTOR signalling pathway. [electronic resource]
Producer: 20200617Description: 19-27 p. digitalISSN:- 1600-0625
- Actins -- metabolism
- Adult
- Cell Proliferation
- Cell Transdifferentiation
- Cicatrix, Hypertrophic -- drug therapy
- Collagen Type I -- metabolism
- Collagen Type III -- metabolism
- Fibroblasts -- cytology
- Glucose
- Humans
- Insulin-Like Growth Factor I -- metabolism
- Linagliptin -- pharmacology
- Muscle, Smooth -- metabolism
- Myofibroblasts -- cytology
- Proto-Oncogene Proteins c-akt -- metabolism
- Signal Transduction
- TOR Serine-Threonine Kinases -- metabolism
- Wound Healing
- Young Adult
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Publication Type: Journal Article
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