Chemical chaperone 4-phenylbutyric acid alleviates the aggregation of human familial pulmonary fibrosis-related mutant SP-A2 protein in part through effects on GRP78. [electronic resource]
Producer: 20190520Description: 3546-3557 p. digitalISSN:- 1879-260X
- A549 Cells
- Animals
- CHO Cells
- Cricetulus
- Dose-Response Relationship, Drug
- Endoplasmic Reticulum Chaperone BiP
- Heat-Shock Proteins -- metabolism
- Humans
- Leupeptins -- pharmacology
- Mutation
- Phenylbutyrates -- pharmacology
- Protein Aggregates -- drug effects
- Pulmonary Fibrosis -- genetics
- Pulmonary Surfactant-Associated Protein A -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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