High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing. [electronic resource]
Producer: 20181217Description: E9944-E9952 p. digitalISSN:- 1091-6490
- Animals
- CRISPR-Cas Systems
- Cells, Cultured
- Endothelial Cells -- cytology
- Gene Editing
- Gene Transfer Techniques
- HEK293 Cells
- Hepatocytes -- cytology
- High-Throughput Screening Assays
- Humans
- Lipids -- chemistry
- Mice
- Mice, Inbred C57BL
- Nanoparticles -- administration & dosage
- RNA, Guide, CRISPR-Cas Systems -- chemistry
- RNA, Messenger -- chemistry
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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