Dual potent ALK and ROS1 inhibitors combating drug-resistant mutants: Synthesis and biological evaluation of aminopyridine-containing diarylaminopyrimidine derivatives. [electronic resource]
Producer: 20181022Description: 322-333 p. digitalISSN:- 1768-3254
- Aminopyridines -- chemistry
- Anaplastic Lymphoma Kinase
- Antineoplastic Agents -- chemistry
- Apoptosis -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Drug Resistance, Neoplasm
- Humans
- Neoplasms -- drug therapy
- Point Mutation
- Protein Kinase Inhibitors -- chemistry
- Protein-Tyrosine Kinases -- antagonists & inhibitors
- Proto-Oncogene Proteins -- antagonists & inhibitors
- Receptor Protein-Tyrosine Kinases -- antagonists & inhibitors
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Publication Type: Journal Article
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