RNF186 impairs insulin sensitivity by inducing ER stress in mouse primary hepatocytes. [electronic resource]
Producer: 20191022Description: 155-162 p. digitalISSN:- 1873-3913
- Animals
- Chemokine CCL2 -- metabolism
- Diabetes Mellitus -- metabolism
- Diet, High-Fat
- Endoplasmic Reticulum Stress
- Eukaryotic Initiation Factor-2B -- metabolism
- Hep G2 Cells
- Hepatocytes -- cytology
- Humans
- Insulin -- metabolism
- Insulin Resistance
- Interleukin-6 -- metabolism
- Liver -- cytology
- Male
- Membrane Proteins -- metabolism
- Mice
- Mice, Inbred C57BL
- Mice, Obese
- Protein Serine-Threonine Kinases -- metabolism
- Taurochenodeoxycholic Acid -- pharmacology
- Transcription Factor CHOP -- metabolism
- Tumor Necrosis Factor-alpha -- metabolism
- Ubiquitin-Protein Ligases -- physiology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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