Ceramide synthase-6 confers resistance to chemotherapy by binding to CD95/Fas in T-cell acute lymphoblastic leukemia. [electronic resource]
Producer: 20191113Description: 925 p. digitalISSN:- 2041-4889
- Apoptosis -- physiology
- Biphenyl Compounds -- pharmacology
- Caspase 8 -- metabolism
- Caspase Inhibitors -- pharmacology
- Cell Line
- Cell Line, Tumor
- Ceramides -- metabolism
- Drug Resistance, Neoplasm -- physiology
- HEK293 Cells
- Humans
- Membrane Proteins -- genetics
- Nitrophenols -- pharmacology
- Oligopeptides -- pharmacology
- Piperazines -- pharmacology
- Precursor T-Cell Lymphoblastic Leukemia-Lymphoma -- drug therapy
- Protein Binding
- Proto-Oncogene Proteins c-bcl-2 -- antagonists & inhibitors
- RNA Interference
- RNA, Small Interfering -- genetics
- Sphingolipids -- metabolism
- Sphingosine N-Acyltransferase -- genetics
- Sulfonamides -- pharmacology
- fas Receptor -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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