A systems-level framework for drug discovery identifies Csf1R as an anti-epileptic drug target. [electronic resource]
Producer: 20190124Description: 3561 p. digitalISSN:- 2041-1723
- Animals
- Anticonvulsants -- pharmacology
- Computer Simulation
- Disease Models, Animal
- Drug Discovery
- Epilepsy -- chemically induced
- Epilepsy, Temporal Lobe -- genetics
- Gene Expression Profiling
- Gene Expression Regulation
- Genetic Association Studies
- High-Throughput Nucleotide Sequencing
- Humans
- Mice
- Molecular Targeted Therapy
- Muscarinic Agonists -- toxicity
- Pilocarpine -- toxicity
- Receptors, Granulocyte-Macrophage Colony-Stimulating Factor -- antagonists & inhibitors
- Sequence Analysis, RNA
- Systems Biology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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