Aspirin Affects Tumor Angiogenesis and Sensitizes Human Glioblastoma Endothelial Cells to Temozolomide, Bevacizumab, and Sunitinib, Impairing Vascular Endothelial Growth Factor-Related Signaling. [electronic resource]
Producer: 20190102Description: e380-e391 p. digitalISSN:- 1878-8769
- Angiogenesis Inhibitors -- pharmacology
- Anti-Inflammatory Agents, Non-Steroidal -- pharmacology
- Antineoplastic Agents -- pharmacology
- Antineoplastic Agents, Alkylating -- pharmacology
- Antineoplastic Agents, Immunological -- pharmacology
- Aspirin -- pharmacology
- Bevacizumab -- pharmacology
- Blotting, Western
- Brain Neoplasms -- blood supply
- Cell Survival -- drug effects
- Drug Synergism
- Endothelial Cells -- drug effects
- Glioblastoma -- blood supply
- Humans
- Hypoxia-Inducible Factor 1, alpha Subunit -- drug effects
- Mitogen-Activated Protein Kinase Kinases -- drug effects
- Proto-Oncogene Proteins c-akt -- drug effects
- Proto-Oncogene Proteins c-bcl-2 -- drug effects
- RNA, Messenger -- drug effects
- Real-Time Polymerase Chain Reaction
- Signal Transduction
- Sunitinib -- pharmacology
- Temozolomide -- pharmacology
- Vascular Endothelial Growth Factor A -- drug effects
- Vascular Endothelial Growth Factor Receptor-1 -- drug effects
- Vascular Endothelial Growth Factor Receptor-2 -- drug effects
- bcl-2-Associated X Protein -- drug effects
- ras Proteins -- drug effects
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Publication Type: Journal Article
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