Peptide-MHC (pMHC) binding to a human antiviral T cell receptor induces long-range allosteric communication between pMHC- and CD3-binding sites. [electronic resource]
Producer: 20190422Description: 15991-16005 p. digitalISSN:- 1083-351X
- Allosteric Regulation
- Animals
- Binding Sites
- Gene Products, tax -- chemistry
- HLA-A2 Antigen -- chemistry
- Human T-lymphotropic virus 1 -- chemistry
- Humans
- Mice
- Molecular Dynamics Simulation
- Protein Binding
- Protein Conformation
- Receptor-CD3 Complex, Antigen, T-Cell -- chemistry
- Receptors, Antigen, T-Cell, alpha-beta -- chemistry
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
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