Intratumor lactate levels reflect HER2 addiction status in HER2-positive breast cancer. [electronic resource]
Producer: 20191210Description: 1768-1779 p. digitalISSN:- 1097-4652
- Animals
- Antineoplastic Agents, Immunological -- therapeutic use
- Biomarkers, Tumor -- antagonists & inhibitors
- Breast Neoplasms -- drug therapy
- Cell Line, Tumor
- Chemotherapy, Adjuvant
- Female
- Gene Expression Regulation, Neoplastic
- Glycolysis
- Humans
- Italy
- Lactic Acid -- metabolism
- Lapatinib -- pharmacology
- Magnetic Resonance Spectroscopy
- Mice
- Oncogene Addiction
- Patient Selection
- Precision Medicine
- Protein Kinase Inhibitors -- therapeutic use
- Receptor, ErbB-2 -- antagonists & inhibitors
- Retrospective Studies
- Trastuzumab -- therapeutic use
- Treatment Outcome
- Up-Regulation
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Publication Type: Journal Article; Multicenter Study; Observational Study; Research Support, Non-U.S. Gov't
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