Clonal heterogeneity influences drug responsiveness in renal cancer assessed by ex vivo drug testing of multiple patient-derived cancer cells. [electronic resource]
Producer: 20190606Description: 1356-1366 p. digitalISSN:- 1097-0215
- 3T3 Cells
- Adult
- Aged
- Animals
- Antineoplastic Agents -- pharmacology
- Carcinoma, Renal Cell -- drug therapy
- Clonal Evolution
- Coculture Techniques
- DNA Copy Number Variations
- Drug Resistance, Neoplasm -- genetics
- Drug Screening Assays, Antitumor -- methods
- Humans
- Kidney Neoplasms -- drug therapy
- Male
- Mice
- Middle Aged
- Mutation
- Primary Cell Culture
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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