New bio-sensitive and biologically active single crystal of pyrimidine scaffold ligand and its gold and platinum complexes: DFT, antimicrobial, antioxidant, DNA interaction, molecular docking with DNA/BSA and anticancer studies. [electronic resource]
Producer: 20190503Description: 144-156 p. digitalISSN:- 1090-2120
- Anti-Bacterial Agents -- chemical synthesis
- Antifungal Agents -- chemical synthesis
- Antineoplastic Agents -- chemical synthesis
- Antioxidants -- chemical synthesis
- Candida albicans -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Coordination Complexes -- chemical synthesis
- DNA, Neoplasm -- chemistry
- Density Functional Theory
- Dose-Response Relationship, Drug
- Drug Screening Assays, Antitumor
- Escherichia coli -- drug effects
- Free Radicals -- antagonists & inhibitors
- Gold -- chemistry
- Humans
- Ligands
- Microbial Sensitivity Tests
- Molecular Docking Simulation
- Molecular Structure
- Platinum -- chemistry
- Pyrimidines -- chemistry
- Serum Albumin, Bovine -- chemistry
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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