Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy. [electronic resource]
Producer: 20190102Description: 3267 p. digitalISSN:- 2041-1723
- Animals
- Antineoplastic Combined Chemotherapy Protocols -- pharmacology
- Cell Line
- Cell Line, Tumor
- Endoribonucleases -- antagonists & inhibitors
- Enzyme Inhibitors -- administration & dosage
- Female
- Gene Expression Profiling
- Gene Expression Regulation, Neoplastic
- HEK293 Cells
- Humans
- Mice, Nude
- Paclitaxel -- administration & dosage
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- RNA Interference
- Triple Negative Breast Neoplasms -- drug therapy
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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