Parthenolide and DMAPT induce cell death in primitive CML cells through reactive oxygen species. [electronic resource]
Producer: 20191119Description: 4899-4912 p. digitalISSN:- 1582-4934
- Apoptosis -- drug effects
- Cell Cycle Checkpoints -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cyclin A -- genetics
- Cyclin D1 -- genetics
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive -- drug therapy
- NF-kappa B -- genetics
- Neoplasm Recurrence, Local -- drug therapy
- Reactive Oxygen Species -- metabolism
- Sesquiterpenes -- pharmacology
- Signal Transduction -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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