Design, Synthesis, and Biological Evaluation of 3-(Imidazo[1,2- a]pyrazin-3-ylethynyl)-4-isopropyl- N-(3-((4-methylpiperazin-1-yl)methyl)-5-(trifluoromethyl)phenyl)benzamide as a Dual Inhibitor of Discoidin Domain Receptors 1 and 2. [electronic resource]
Producer: 20191015Description: 7977-7990 p. digitalISSN:- 1520-4804
- Acute Lung Injury -- chemically induced
- Animals
- Anti-Inflammatory Agents -- chemical synthesis
- Discoidin Domain Receptor 1 -- antagonists & inhibitors
- Discoidin Domain Receptor 2 -- antagonists & inhibitors
- Drug Design
- Humans
- Lipopolysaccharides -- toxicity
- Male
- Mice
- Mice, Inbred C57BL
- Pneumonia -- chemically induced
- Rats
- Rats, Sprague-Dawley
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Publication Type: Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
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