Inhibiting Notch1 enhances immunotherapy efficacy in melanoma by preventing Notch1 dependent immune suppressive properties. [electronic resource]
Producer: 20190930Description: 144-151 p. digitalISSN:- 1872-7980
- Animals
- Antineoplastic Combined Chemotherapy Protocols -- pharmacology
- CD8-Positive T-Lymphocytes -- immunology
- Cell Line, Tumor
- Cytokines -- genetics
- Female
- Humans
- Immunotherapy -- methods
- Ipilimumab -- administration & dosage
- Melanoma, Experimental -- genetics
- Mice, Inbred C57BL
- Myeloid-Derived Suppressor Cells -- immunology
- Nivolumab -- administration & dosage
- RNA Interference
- Receptor, Notch1 -- genetics
- T-Lymphocytes, Regulatory -- immunology
- Treatment Outcome
- Tumor Burden -- drug effects
- Tumor Microenvironment -- drug effects
No physical items for this record
Publication Type: Journal Article; Research Support, N.I.H., Extramural
There are no comments on this title.
Log in to your account to post a comment.