Detection of EGFR mutations in plasma circulating tumour DNA as a selection criterion for first-line gefitinib treatment in patients with advanced lung adenocarcinoma (BENEFIT): a phase 2, single-arm, multicentre clinical trial. [electronic resource]
Producer: 20190531Description: 681-690 p. digitalISSN:- 2213-2619
- Adenocarcinoma -- drug therapy
- Administration, Oral
- Adult
- Aged
- Biomarkers, Tumor -- blood
- Circulating Tumor DNA -- blood
- DNA Mutational Analysis -- methods
- Disease-Free Survival
- Female
- Gefitinib -- administration & dosage
- Genes, Tumor Suppressor
- Genes, erbB-1
- Humans
- Intention to Treat Analysis
- Lung Neoplasms -- drug therapy
- Male
- Middle Aged
- Mutation
- Protein Kinase Inhibitors -- administration & dosage
- Sensitivity and Specificity
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Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
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