Loss of the novel Vcp (valosin containing protein) interactor Washc4 interferes with autophagy-mediated proteostasis in striated muscle and leads to myopathy in vivo. [electronic resource]
Producer: 20191029Description: 1911-1927 p. digitalISSN:- 1554-8635
- Animals
- Animals, Genetically Modified
- Autophagy -- genetics
- Embryo, Nonmammalian
- Gene Deletion
- HEK293 Cells
- Humans
- Intracellular Signaling Peptides and Proteins -- genetics
- Male
- Mice
- Muscle, Skeletal -- metabolism
- Muscle, Striated -- metabolism
- Muscular Diseases -- genetics
- Protein Binding
- Proteostasis -- genetics
- Valosin Containing Protein -- metabolism
- Zebrafish -- embryology
- Zebrafish Proteins -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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