In vitro and ex vivo anti-fibrotic effects of LY2109761, a small molecule inhibitor against TGF-β. [electronic resource]
Producer: 20190314Description: 127-137 p. digitalISSN:- 1096-0333
- Adenosine Triphosphate -- metabolism
- Animals
- Cell Line
- Collagen Type I -- antagonists & inhibitors
- Down-Regulation
- Fibrosis -- drug therapy
- Gene Expression -- drug effects
- Humans
- In Vitro Techniques
- Liver -- drug effects
- Male
- Phosphorylation
- Pyrazoles -- pharmacology
- Pyrroles -- pharmacology
- Rats
- Rats, Wistar
- Smad1 Protein -- antagonists & inhibitors
- Smad2 Protein -- antagonists & inhibitors
- Tissue Inhibitor of Metalloproteinase-2 -- antagonists & inhibitors
- Transforming Growth Factor beta -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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