Sporadic Parkinson's disease derived neuronal cells show disease-specific mRNA and small RNA signatures with abundant deregulation of piRNAs. [electronic resource]
Producer: 20190604Description: 58 p. digitalISSN:- 2051-5960
- Adult
- Aged
- CREB-Binding Protein -- genetics
- Cell Differentiation -- physiology
- Cohort Studies
- Down-Regulation -- physiology
- Epigenomics
- Female
- Fibroblasts -- metabolism
- Humans
- Induced Pluripotent Stem Cells -- metabolism
- Male
- MicroRNAs -- genetics
- Middle Aged
- Neurons -- metabolism
- Nitric Oxide Synthase Type I -- genetics
- Parkinson Disease -- pathology
- Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha -- genetics
- RNA, Messenger -- genetics
- RNA, Small Interfering -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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