Glucosylceramide synthase inhibition with lucerastat lowers globotriaosylceramide and lysosome staining in cultured fibroblasts from Fabry patients with different mutation types. [electronic resource]
Producer: 20190328Description: 3392-3403 p. digitalISSN:- 1460-2083
- 1-Deoxynojirimycin -- analogs & derivatives
- Cell Line
- Fabry Disease -- drug therapy
- Female
- Fibroblasts -- drug effects
- Genotype
- Glucosyltransferases -- antagonists & inhibitors
- Humans
- Kidney -- drug effects
- Lysosomes -- genetics
- Male
- Mutation -- genetics
- Trihexosylceramides -- genetics
- alpha-Galactosidase -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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