Plant galactolipid dLGG suppresses lung metastasis of melanoma through deregulating TNF-α-mediated pulmonary vascular permeability and circulating oxylipin dynamics in mice. [electronic resource]
Producer: 20190314Description: 3248-3261 p. digitalISSN:- 1097-0215
- Animals
- Antineoplastic Agents, Phytogenic -- pharmacology
- Biomarkers, Tumor -- metabolism
- Capillary Permeability -- physiology
- Cell Proliferation -- drug effects
- Docosahexaenoic Acids -- pharmacology
- Epithelial-Mesenchymal Transition
- Focal Adhesion Kinase 2 -- metabolism
- Glucosides -- pharmacology
- Glycerol -- analogs & derivatives
- Humans
- Lung Neoplasms -- prevention & control
- Male
- Melanoma, Experimental -- secondary
- Metabolomics
- Mice, Inbred C57BL
- Neoplasm Invasiveness -- prevention & control
- Oxylipins -- blood
- Plants -- chemistry
- Pulmonary Artery -- physiology
- Pulmonary Veins -- physiology
- Signal Transduction
- Tight Junctions -- drug effects
- Tumor Microenvironment
- Tumor Necrosis Factor-alpha -- metabolism
- src-Family Kinases -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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