Alleviation of hepatic fibrosis and autophagy via inhibition of transforming growth factor-β1/Smads pathway through shikonin. [electronic resource]
Producer: 20190503Description: 263-276 p. digitalISSN:- 1440-1746
- Alanine Transaminase -- blood
- Animals
- Anti-Inflammatory Agents, Non-Steroidal -- pharmacology
- Aspartate Aminotransferases -- blood
- Autophagy -- drug effects
- Disease Models, Animal
- Down-Regulation -- drug effects
- Extracellular Matrix -- metabolism
- Hepatic Stellate Cells -- physiology
- Liver Cirrhosis -- metabolism
- Male
- Matrix Metalloproteinase 2 -- metabolism
- Mice
- Mice, Inbred C57BL
- Naphthoquinones -- pharmacology
- Signal Transduction -- drug effects
- Smad Proteins, Receptor-Regulated -- antagonists & inhibitors
- Tissue Inhibitor of Metalloproteinase-1 -- metabolism
- Transforming Growth Factor beta1 -- antagonists & inhibitors
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Publication Type: Journal Article
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