Engineered MBP-specific human Tregs ameliorate MOG-induced EAE through IL-2-triggered inhibition of effector T cells. [electronic resource]
Producer: 20190625Description: 77-86 p. digitalISSN:- 1095-9157
- Animals
- Autoimmunity
- Bystander Effect
- Cells, Cultured
- Disease Models, Animal
- Encephalomyelitis, Autoimmune, Experimental -- genetics
- Forkhead Transcription Factors -- metabolism
- Genetic Engineering
- Genetic Predisposition to Disease
- HLA-DR Serological Subtypes -- genetics
- Humans
- Immunotherapy, Adoptive -- methods
- Interleukin-2 -- metabolism
- Lymphocyte Activation
- Mice
- Mice, Transgenic
- Multiple Sclerosis -- genetics
- Myelin Basic Protein -- immunology
- Myelin-Oligodendrocyte Glycoprotein -- immunology
- Polymorphism, Genetic
- Receptors, Antigen, T-Cell -- genetics
- T-Cell Antigen Receptor Specificity
- T-Lymphocyte Subsets -- immunology
- T-Lymphocytes, Regulatory -- immunology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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